Laboratory Safety Manual
This on-line Laboratory Safety Manual (LSM) provides information regarding protection from health hazards associated with the laboratory environment in accordance with applicable California Occupational Safety and Health Administration (Cal-OSHA) regulations, including the "Chemical Hygiene Plan" requirements specified in 8 CCR 5191. The LSM serves as a resource for identifying and evaluating the nature of potential laboratory hazards, as well as determining appropriate hazard controls. The information in this manual applies to all laboratories that use, store or handle potentially hazardous materials and all personnel who work in these facilities.
This on-line manual, in conjunction with your lab-specific information, replaces the printed Chemical Hygiene Plan (the former Appendix J of the IIPP "slug" binder). The laboratory Injury & Illness Prevention Program is located in your lab at the beginning of the "Slug" binder, as well as here - Injury and Illness Prevention Program.
The Laboratory Safety Manual was last reviewed on May 17, 2016. Revisions are made continuously throughout the year by EH&S Staff.
Because each lab is different, and processes change routinely, each lab has the responsibility to maintain lab-specific safety information and documentation. The Principal Investigator is responsible for documenting lab-specific information, including:
- Laboratory Safety Fundamentals training for all personnel working in the lab
- Lab-Specific Training Checklist completion for all personnel working in the lab
- Laboratory Hazard Assessment Tool (LHAT) personal protective equipment assessment for each lab
- Standard Operating Procedures (SOPs) for processes that use particularly hazardous substances, including "Operations Requiring Prior Approval"
- Laboratory Self-Inspection Checklist used by the lab group to conduct periodic inspections
Lab-specific information must be reviewed and approved by the Principal Investigator when new processes are added, existing processes change significantly, or at least annually.
General Lab Hazard and Safety Information
The following document, excerpted and edited from the UCLA Chemical Hygiene Plan, provides general chemical hazard information, as well as exposure control and safety information.
Pyrophoric Chemical Information
Pyrophoric materials can ignite spontaneously on contact with air. All work conducted with these materials must follow an approved SOP addressing the specific process used in the lab (including such points as specific hood/area, transfer techniques, PPE required, no lone worker policy, etc.). The SOP must specify the use of a flame-resistant or Nomex lab coat and gloves. The SOP must also clearly describe procedures to be taken in the event of an emergency. This SOP must be reviewed, approved, and signed by the PI.
Researchers working in UCSC Laboratories have the right to report workplace hazards without the fear of reprisal (8 CCR 3203 (a)(3)). Principal Investigators are responsible for informing researchers how to access and submit a Hazard Alert form by having hardcopies available or directing individuals to the EH&S on-line form. Hazard Alert forms, whether hardcopy or electronic, can be submitted anonymously.
"Prudent Practices in the Laboratory: Handling and Management of Chemical Hazards," National Acadamies Press, 2011
Title 8, California Code of Regulations, Section 5191 (8 CCR 5191), "Occupational Exposure to Hazardous Chemicals in Laboratories"
Title 8, California Code of Regulations, Section 3203 (8 CCR 3203), "Injury and Illness Prevention Program"
"Enviro-Health Links - Laboratory Safety," National Library of Medicine
UC Santa Cruz acknowledges the assistance of the UCLA Office of Environment, Health & Safety, whose Chemical Hygiene Plan (December 2011) and webpage (https://www.ehs.ucla.edu/doc/LabSafetyManual.pdf/view) have served as useful resources.